Double-Blind, Parallel, Randomized Clinical Trial to Determine the Efficacy in Improving Cosmetic Attributes of Facial Skin when Using Cupron (Copper-Oxide Containing) Pillowcases

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Summary

* Fifty-seven individuals, (55 women and two men), completed a 4 week, double blind, parallel, randomized clinical study. The participants used either copper-oxide containing pillowcases or pillowcases not containing copper-oxide (the “placebo control pillow cases”). Photographs were taken by a professional photographer of each participant at three times: The beginning (baseline) of the Trial, and at 2 and 4 weeks after the commencement of the Trial.

* An expert grader (dermatologist) evaluated the face for the effect on the following cosmetic facial skin attributes of those individuals using both the copper-oxide containing pillowcases and the placebo control pillowcases: wrinkles; crowsfeet/fine lines; blemishes; skin glow; texture; and general appearance. These qualities were evaluated at the baseline, 2, and 4 weeks.

Conclusions

* There was a statistically significant reduction of the appearance of facial wrinkles and crowsfeet/fine lines and statistically significant improvement in the texture and overall appearance of facial skin when consistently sleeping for 4 weeks on 1% (weight/weight) copper-oxide containing pillowcases (the Cupron pillowcases) versus the placebo control pillowcases. In most trial participants, this statistically significant effect was already noticeable within 2 weeks of using the copper-oxide containing pillowcases.